Project Description
EPRUI Biotech has developed a vancomycin purification chromatography medium which is specially designed for high efficient separation and purification of Vancomycin.
EPRUI vanco chromatography media is a spherical and monodisperse microspheres with precisely controlled particle size and optimized pore structure. EPRUI Vanco chromatography media provides excellent selectivity, high retention capacity, low back pressure, minimal elution volume, and high recovery yield of Vancomycin. In comparison with other vancomycin purification chromatography available in the market, EPRUI Vanco possesses much higher efficiency in removing dechlorovancomycin.
EPRUI Vanco media is very stable in almost all aqueous solutions including NaOH (1 M) and HCl (1 M), and organic solvents, such as IPA, DMSO, THF, Methanol, Acetone, Acetonitrile, guanidine hydrochloride (6 M), etc.
Features & Benefits
Features
- Spherical morphology
- Highly uniform particle size
- Optimized pore structure
- Good PH Stability
- No filter impurities
- High rigidity
- Large scale production capacity
Benefits
- Easy column packing
- High selectivity and loading capacity
- Long lifetime
- Low back pressure
- Consistent high quality
- High purity
Breakthrough Curves for Vancomycin
vs Competitor H
Chromatography Data for Vancomycin
Resin | Sample Loading capacity(mg/ml) | Purity | Yield |
---|---|---|---|
EPRUI Vanco | 36.7 | ≥95% | 81.4% |
Competitor H | 36.7 | ≥95% | 43.5% |
Dynamic Binding Capacity of EPRUI
Dynamic Binding Capacity of EPRUI Vancomycin Purification Chromatography Media
EPRUI Vanco exhibits much higher dynamic binding capacity for Vancomycin and leads to a much higher purity and recovery yield than competitor’s adsorbents as shown below.
Resin | 10% Capacity (mg/ml) | 100% Capacity(mg/ml) |
---|---|---|
EPRUI-Vanco | 27.5 | 48 |
Competitor H | 9.6 | 46 |
Specifications
Matrix | Spherical monodisperse porous PS/DVB |
Particle Size | 40um |
Coefficient of Variation | <3% |
Pore Size | 300A |
Pore Volume | ~1.6cm3/g |
Surface Area | 850m2/g |
PH Stability | 1-14 |
Operating Temperature | 4-60℃ |
Max Operating Pressure | 40 bar |
Product List
Item | Matrix | Particle Size | Pore Size | CV. |
---|---|---|---|---|
EPRUI Vanco | PS/DVB | 40um | 300A | <3% |